| I．対象データ：1966年〜2002年11月 |
|
| 疾患：肝細胞癌に限定（動物実験を除く） |
|
| 言語：英語・日本語文献に限定 |
|
| 収載誌発行年：1982年以降（手術領域のみ1980〜2001年） |
|
| II．領域別検索式 |
|
| 【予防】 |
| File 155：MEDLINE（R） 1966─2002/Oct W4 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
PREVENTIVE MEDICINE! OR CHEMOPREVENTION! OR PREVENT? OR PROPHYLA? |
|
| S9 |
S7 AND S1（L）PC |
|
| S10 |
（S7 AND S8）NOT S9 |
|
| S11 |
HEPATITIS C!（L）（TH OR DT）/MAJ |
|
| S12 |
S11/HUMAN OR（S11 NOT ANIMAL/GS） |
|
| S13 |
S12/ENG OR S12 AND LA＝JAPANESE |
|
| S14 |
S13 AND PY＝＞1982 |
|
| S15 |
S9 OR S10 |
|
| S16 |
DT＝（GUIDELINE＋PRACTICE GUIDELINE＋CONSENSUS DEVELOPMENT CONFERENCE?）＋（GUIDELINES＋PRACTICE GUIDELINES）/DE＋ GUIDELINE?/TI＋RECOMMENDATION?/TI＋EVIDENCE?（W）BASED/TI |
|
| S17 |
CLINICAL PROTOCOLS/DE＋PATIENT CARE PLANNING!＋（CLINICAL＋CRITICAL）（1W）（PATH＋PATHS＋PATHWAY?）/TI＋（CLINICAL＋TREATMENT?）（2N）PROTOCOL?/TI＋CARE（1N）PLANNING?/TI＋（GOOD（1W）CLINICAL（1W）PRACTICE?）/TI |
|
| S18 |
S16 OR S17 |
|
| S19 |
SYSTEMATIC（1W）（REVIEW?＋OVERVIEW?）＋PEER REVIEW! |
|
| S20 |
JN＝（COCHRANE DATABASE SYST REV＋ACP JOURNAL CLUB＋ACP J CLUB＋HEALTH TECHNOL ASSESS＋EVID REP TECHNOL ASSESS?） |
|
| S21 |
S19 OR S20 |
|
| S22 |
DT＝META─ANALYSIS＋META─ANALYSIS/DE＋（METAANALY?＋META（W）ANALY?）/TI |
|
| S23 |
DT＝RANDOMIZED CONTROLLED TRIAL＋RANDOMIZED CONTROLLED TRIALS/DE＋RANDOM ALLOCATION/DE＋RANDOM?＋DOUBLE-BLIND METHOD/DE＋SINGLE-BLIND METHOD/DE＋（SINGL?＋DOUBLE?＋TREBL?＋TRIPL?）（W）（BLIND?＋MASK?） |
|
| S24 |
DT＝CONTROLLED CLINICAL TRIAL＋CONTROLLED CLINICAL TRIALS!＋PLACEBOS/DE＋SINGLE-BLIND METHOD/DE＋CROSS-OVER STUDIES/ DE＋PLACEBO?＋COMPARATIVE STUDY/GS＋CONTROL?（1W）（TRIAL?＋STUD?） |
|
| S25 |
DT＝CLINICAL TRIAL?＋CLINICAL TRIALS!/DE＋（CLINICAL（1W）TRIAL?）/TI |
|
| S26 |
DT＝MULTICENTER STUDY＋MULTICENTER STUDIES/DE＋（MULTICENT?＋MULTI（W）CENT?）/TI |
|
| S27 |
COHORT STUDIES! |
|
| S28 |
CASE-CONTROL STUDIES!＋MATCHED-PAIR ANALYSIS/DE |
|
| S29 |
DT＝REVIEW OF REPORTED CASES＋CASE（W）SERIES/TI |
|
| S30 |
CASE REPORT/GS |
|
| S31 |
DT＝REVIEW?＋REVIEW LITERATURE/DE |
|
| S32 |
S18 OR S21：S31 |
|
| S33 |
S15 AND S32 |
|
| S34 |
S14 NOT S15 |
|
| S35 |
S18 OR S21：S25 |
|
| S36 |
S34 AND S35 |
1,100 |
| S37 |
S33 AND S9 |
146 |
| S38 |
S33 AND S10 |
584 |
| S39 |
S36 OR S37 OR S38 |
1,830 |
| 【診断：腫瘍マーカー】 |
| File 155：MEDLINE（R）1966─2002/Oct W3 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/MAJ |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA?/TI OR HEPATOMA? /TI |
|
| S3 |
HCC AND LIVER NEOPLASMS!/MAJ |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR （S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
S7 AND TUMOR MARKERS, BIOLOGICAL!/MAJ |
|
| S9 |
S7 AND（ALPHAFETOPROTEIN? OR ALPHA（）FETOPROTEIN? OR AFP） |
|
| S10 |
S7 AND（DES（）GAMMA（）CARBOXYPROTHROMBIN OR DESGAMMA（）CARBOXY（）PROTHROMBIN OR DES（）GAMMA（）CARBOXY（）PROTHROMBIN） |
|
| S11 |
S7 AND DCP AND PROTHROMBIN |
|
| S12 |
PROTEIN?（2N）VITAMIN（）K（1W）（ABSENCE OR ANTAGONIST?）OR （PIVKA（）II OR PIVKA（）2） |
|
| S13 |
S7 AND S8 |
|
| S14 |
（S7 AND（S9 OR S10 OR S11 OR S12））NOT S13 |
|
| S15 |
DT＝（GUIDELINE＋PRACTICE GUIDELINE＋CONSENSUS DEVELOPMENT CONFERENCE?）＋（GUIDELINES＋PRACTICE GUIDELINES）/DE＋GUIDELINE?/TI＋RECOMMENDATION?/TI＋EVIDENCE?（W）BASED/TI |
|
| S16 |
CLINICAL PROTOCOLS/DE＋PATIENT CARE PLANNING!＋（CLINICAL＋CRITICAL）（1W）（PATH＋PATHS＋PATHWAY?）/TI＋（CLINICAL＋TREATMENT?）（2N）PROTOCOL?/TI＋CARE（1N）PLANNING?/TI＋（GOOD（1W）CLINICAL（1W）PRACTICE?）/TI |
|
| S17 |
S15 OR S16 |
|
| S18 |
SYSTEMATIC（1W）（REVIEW?＋OVERVIEW?）＋PEER REVIEW! |
|
| S19 |
JN＝（COCHRANE DATABASE SYST REV＋ACP JOURNAL CLUB＋ACP J CLUB＋HEALTH TECHNOL ASSESS＋EVID REP TECHNOL ASSESS?） |
|
| S20 |
S18 OR S19 |
|
| S21 |
DT＝META-ANALYSIS＋META-ANALYSIS/DE＋（METAANALY?＋META（W）ANALY?）/TI |
|
| S22 |
DT＝RANDOMIZED CONTROLLED TRIAL＋RANDOMIZED CONTROLLED TRIALS/DE＋RANDOM ALLOCATION/DE＋RANDOM?＋DOUBLE-BLIND METHOD |
|
| S23 |
DT＝CONTROLLED CLINICAL TRIAL＋CONTROLLED CLINICAL TRIALS!＋PLACEBOS/DE＋SINGLE─BLIND METHOD/DE＋CROSS-OVER STUDIES/DE＋PLACEBO?＋COMPARATIVE STUDY/GS＋CONTROL?（1W）（TRIAL?＋STUD?） |
|
| S24 |
DT＝CLINICAL TRIAL?＋CLINICAL TRIALS!/DE＋（CLINICAL（1W）TRIAL?）/TI |
|
| S25 |
DT＝MULTICENTER STUDY＋MULTICENTER STUDIES/DE＋（MULTICENT?＋MULTI（W）CENT?）/TI |
|
| S26 |
COHORT STUDIES! |
|
| S27 |
CASE-CONTROL STUDIES!＋MATCHED-PAIR ANALYSIS/DE |
|
| S28 |
DT＝REVIEW OF REPORTED CASES＋CASE（W）SERIES/TI |
|
| S29 |
CASE REPORT/GS |
|
| S30 |
DT＝REVIEW?＋REVIEW LITERATURE/DE |
|
| S31 |
S17 OR S20：S30 |
|
| S32 |
S13 AND S31 |
280 |
| S33 |
S14 AND S31 |
849 |
| S34 |
S32 OR S33 |
1,129 |
| 【診断：画像診断（US以外）】 |
| File 155：MEDLINE（R） 1966─2002/Oct W4 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
S7 AND（S1（L）（RA OR RI）OR LIVER!（L）（RA OR RI）） |
|
| S9 |
S7 AND DIAGNOSTIC IMAGING! |
|
| S10 |
S7 AND IMAGE PROCESSING, COMPUTER-ASSISTED! |
|
| S11 |
S7 AND RADIOLOGY! AND S1（L）DI |
|
| S12 |
S7 AND（CT OR TOMOGRAPH? OR MRI OR IMAG? OR ANGIOGRA? OR SCINT?）/TI |
|
| S13 |
S8：S12 |
|
| S14 |
DT＝（GUIDELINE＋PRACTICE GUIDELINE＋CONSENSUS DEVELOPMENT CONFERENCE?）＋（GUIDELINES＋PRACTICE GUIDELINES）/DE＋GUIDELINE?/TI＋RECOMMENDATION?/TI＋EVIDENCE?（W）BASED/TI |
|
| S15 |
CLINICAL PROTOCOLS/DE＋PATIENT CARE PLANNING!＋（CLINICAL＋CRITICAL）（1W）（PATH＋PATHS＋PATHWAY?）/TI＋（CLINICAL＋TREATMENT?）（2N）PROTOCOL?/TI＋CARE（1N）PLANNING?/TI＋（GOOD（1W）CLINICAL（1W）PRACTICE?）/TI |
|
| S16 |
S14 OR S15 |
|
| S17 |
SYSTEMATIC（1W）（REVIEW?＋OVERVIEW?）＋PEER REVIEW! |
|
| S18 |
JN＝（COCHRANE DATABASE SYST REV＋ACP JOURNAL CLUB＋ACP J CLUB＋HEALTH TECHNOL ASSESS＋EVID REP TECHNOL ASSESS?） |
|
| S19 |
S17 OR S18 |
|
| S20 |
DT＝META-ANALYSIS＋META-ANALYSIS/DE＋（METAANALY?＋META（W）ANALY?）/TI |
|
| S21 |
DT＝RANDOMIZED CONTROLLED TRIAL＋RANDOMIZED CONTROLLED TRIALS/DE＋RANDOM ALLOCATION/DE＋RANDOM?＋DOUBLE-BLIND METHOD/DE＋SINGLE-BLIND METHOD/DE＋（SINGL?＋DOUBLE?＋TREBL?＋TRIPL?）（W）（BLIND?＋MASK?） |
|
| S22 |
DT＝CONTROLLED CLINICAL TRIAL＋CONTROLLED CLINICAL TRIALS!＋PLACEBOS/DE＋SINGLE-BLIND METHOD/DE＋CROSS-OVER STUDIES/ DE＋PLACEBO?＋COMPARATIVE STUDY/GS＋CONTROL?（1W）（TRIAL?＋STUD?） |
|
| S23 |
DT＝CLINICAL TRIAL?＋CLINICAL TRIALS!/DE＋（CLINICAL（1W）TRIAL?）/TI |
|
| S24 |
DT＝MULTICENTER STUDY＋MULTICENTER STUDIES/DE＋（MULTICENT?＋MULTI（W）CENT?）/TI |
|
| S25 |
COHORT STUDIES! |
|
| S26 |
CASE-CONTROL STUDIES!＋MATCHED-PAIR ANALYSIS/DE |
|
| S27 |
DT＝REVIEW OF REPORTED CASES＋CASE（W）SERIES/TI |
|
| S28 |
S16 OR S19：S27 |
|
| S29 |
S13 AND S28 |
1,075 |
| S30 |
S29 NOT CASE REPORT/GS |
941 |
| S31 |
S30 NOT DT＝（LETTER OR NEWS OR COMMENT OR EDITORIAL） |
937 |
| 【診断：超音波（US）】 |
| File 155：MEDLINE（R） 1966─2002/Oct W3 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
S7 AND（S1（L）US OR LIVER!（L）US） |
|
| S9 |
S7 AND（ULTRASONOGRAPHY! OR ULTRASONICS!） |
|
| S10 |
S7 AND（ULTRASOUND? OR ENDOSONOGR? OR SONOGR?）/TI |
|
| S11 |
S8：S10 |
1,022 |
| 【治療：手術（切除術・移植）】 |
| File 155：MEDLINE（R） 1966─2002/Sep W4 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG |
|
| S7 |
S6 AND PY＝1980：2001 |
|
| S8 |
S7 NOT CASE REPORT/GS |
|
| S9 |
S8 NOT（DT＝REVIEW? OR REVIEW LITERATURE/DE） |
|
| S10 |
S8 AND SYSTEMATIC（1W）（REVIEW?＋OVERVIEW?）/TI OR S9 |
|
| S11 |
S1（L）SU |
|
| S12 |
LIVER NEOPLASMS!（L）SU OR LIVER!（L）SU |
|
| S13 |
SURGICAL PROCEDURES, OPERATIVE! NOT TRANSPLANTATION! |
|
| S14 |
HEPATECTOM? OR RESECT? OR SURG? OR OPERAT? |
|
| S15 |
S10 AND（S11 OR S12 OR S13 OR S14） |
|
| S16 |
S15 AND S1/MAJ OR S15 AND（HCC OR HEPATOCELL? OR HEPATOMA?）/TI |
|
| S17 |
S15 AND（S11/MAJ OR S12/MAJ OR S13/MAJ OR S14/TI） |
|
| S18 |
S16 AND S17 |
|
| S19 |
S18 NOT DT＝（COMMENT OR LETTER OR NEWS OR EDITORIAL） |
|
| S20 |
LIVER TRANSPLANTATION OR LIVER!（L）TR |
|
| S21 |
（HEPAT? OR LIVER OR HCC）（3N）（TRANSPLANT? OR GRAFT?） |
|
| S22 |
S10 AND（S20 OR S21） |
|
| S23 |
S22 AND S1/MAJ OR S22 AND（HCC OR HEPATOCELL? OR HEPATOMA?）/TI |
|
| S24 |
S23 AND（S20/MAJ OR S21/TI） |
|
| S25 |
S23 AND S24 |
|
| S26 |
S25 NOT DT＝（COMMENT OR LETTER OR NEWS OR EDITORIAL） |
200 |
| 【治療：化学療法】 |
| File 155：MEDLINE（R） 1966─2002/Oct W3 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
S7 AND S1（L）DT |
|
| S9 |
S7 AND DRUG THERAPY! |
|
| S10 |
S7 AND CHEMOTHERAP?/TI |
|
| S11 |
S7 AND ANTINEOPLASTIC ﾒANDﾓ IMMUNOSUPPRESSIVE AGENTS!（L）TU |
|
| S12 |
S8：S11 |
|
| S13 |
DT＝（GUIDELINE＋PRACTICE GUIDELINE＋CONSENSUS DEVELOPMENT CONFERENCE?）＋（GUIDELINES＋PRACTICE GUIDELINES）/DE＋GUIDEL INE?/TI＋RECOMMENDATION?/TI＋EVIDENCE?（W）BASED/TI |
|
| S14 |
CLINICAL PROTOCOLS/DE＋PATIENT CARE PLANNING!＋（CLINICAL＋CRITICAL）（1W）（PATH＋PATHS＋PATHWAY?）/TI＋（CLINICAL＋TREATMENT?）（2N）PROTOCOL?/TI＋CARE（1N）PLANNING?/TI＋（GOOD（1W）CLINICAL（1W）PRACTICE?）/TI |
|
| S15 |
S13 OR S14 |
|
| S16 |
SYSTEMATIC（1W）（REVIEW?＋OVERVIEW?）＋PEER REVIEW! |
|
| S17 |
JN＝（COCHRANE DATABASE SYST REV＋ACP JOURNAL CLUB＋ACP J CLUB＋HEALTH TECHNOL ASSESS＋EVID REP TECHNOL ASSESS?） |
|
| S18 |
S16 OR S17 |
|
| S19 |
DT＝META-ANALYSIS＋META-ANALYSIS/DE＋（METAANALY?＋META（W）ANALY?）/TI |
|
| S20 |
DT＝RANDOMIZED CONTROLLED TRIAL＋RANDOMIZED CONTROLLED TRIALS/DE＋RANDOM ALLOCATION/DE＋RANDOM?＋DOUBLE-BLIND METHOD/DE＋SINGLE-BLIND METHOD/DE＋（SINGL?＋DOUBLE?＋TREBL?＋TRIPL?）（W）（BLIND?＋MASK?） |
|
| S21 |
DT＝CONTROLLED CLINICAL TRIAL＋CONTROLLED CLINICAL TRIALS!＋PLACEBOS/DE＋SINGLE-BLIND METHOD/DE＋CROSS-OVER STUDIES/ DE＋PLACEBO?＋COMPARATIVE STUDY/GS＋CONTROL?（1W）（TRIAL?＋STUD?） |
|
| S22 |
DT＝CLINICAL TRIAL?＋CLINICAL TRIALS!/DE＋（CLINICAL（1W）TRIAL?）/TI |
|
| S23 |
DT＝MULTICENTER STUDY＋MULTICENTER STUDIES/DE＋（MULTICENT?＋MULTI（W）CENT?）/TI |
|
| S24 |
COHORT STUDIES! |
|
| S25 |
CASE-CONTROL STUDIES!＋MATCHED-PAIR ANALYSIS/DE |
|
| S26 |
DT＝REVIEW OF REPORTED CASES＋CASE（W）SERIES/TI |
|
| S27 |
S15 OR S18：S26 |
|
| S28 |
S12 AND S27 |
855 |
| 【治療：TAE】 |
| File 155：MEDLINE（R） 1966─2002/Nov W3 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
S4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
EMBOLIZATION, THERAPEUTIC! |
|
| S8 |
TAE OR（TRANSCATHETER? OR TRANSARTER?）（3N）（EMBOLI? OR CHEMOEMBOLI?） |
|
| S9 |
S6 AND（S7 OR S8） |
|
| S10 |
S9 AND PY＝＞1982 |
1,669 |
| 【治療：ablation他】 |
| File 155：MEDLINE（R） 1966─2002/Sep W5 |
| Set |
Description |
| S1 |
CARCINOMA, HEPATOCELLULAR/DE |
|
| S2 |
（HEPATOCELL? OR LIVER（）CELL）（1N）CARCINOMA? OR HEPATOMA? |
|
| S3 |
HCC AND LIVER NEOPLASMS! |
|
| S4 |
S1：S3 |
|
| S5 |
4/HUMAN OR（S4 NOT ANIMAL/GS） |
|
| S6 |
S5/ENG OR S5 AND LA＝JAPANESE |
|
| S7 |
S6 AND PY＝＞1982 |
|
| S8 |
ETHANOL/DE OR ETHANOL（2N）（PERCUTAN? OR INJECT?） |
|
| S9 |
（PEI OR PEIT OR EIT）AND ETHANOL |
|
| S10 |
S7 AND（S8 OR S9） |
|
| S11 |
MICROWAVES/DE OR MICROWAVE?（2N）（PERCUTAN? OR COAGULAT?） |
|
| S12 |
（PMCT OR MCT）AND MICROWAVE? |
|
| S13 |
S7 AND（S11 OR S12） |
|
| S14 |
ELECTROCOAGULATION! OR RADIO WAVES/DE OR ABLAT? |
|
| S15 |
RADIO（1W）FREQUENC? OR RADIOFREQUENC? OR RFA AND RADIO |
|
| S16 |
S7 AND（S14 OR S15） |
|
| S17 |
S10 OR S13 OR S16 |
945 |
